CYP51A1 Full-Length MS Protein Standard


Product Description:

Name CYP51A1 Full-Length MS Protein Standard
Cat# CPFL307078
Protein NameCYP51A1 cytochrome P450, family 51, subfamily A, polypeptide 1 [ Homo sapiens ]
SymbolCYP51A1
SynonymsCP51; CYP51; CYPL1; LDM; P450-14DM; P450L1
AccessionNM_000786
Cytogenetic7q21.2
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW57.1 kDa
Expression TrueORF CloneRC207078
DescriptionCYP51A1 Full-Length MS Protein Standard (NP_000777), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum protein participates in the synthesis of cholesterol by catalyzing the removal of the 14alpha-methyl group from lanosterol. Homologous genes are found in all three eukaryotic phyla, fungi, plants, and animals, suggesting that this is one of the oldest cytochrome P450 genes. Two transcript variants encoding different isoforms have been found for this gene.

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