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ARFGAP1 Full-Length MS Protein Standard

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Product Description


NameARFGAP1 Full-Length MS Protein Standard
Cat#CPFL306987
Protein NameADP-ribosylation factor GTPase activating protein 1
SymbolARFGAP1
SynonymsARF1GAP; HRIHFB2281
AccessionNM_175609
Cytogenetic20q13.33
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionARFGAP1 Full-Length MS Protein Standard (NP_783202), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. The protein encoded by this gene is a GTPase-activating protein, which associates with the Golgi apparatus and which interacts with ADP-ribosylation factor 1. The encoded protein promotes hydrolysis of ADP-ribosylation factor 1-bound GTP and is required for the dissociation of coat proteins from Golgi-derived membranes and vesicles. Dissociation of the coat proteins is required for the fusion of these vesicles with target compartments. The activity of this protein is stimulated by phosphoinosides and inhibited by phosphatidylcholine. Alternative splicing results in multiple transcript variants.

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