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CUL4B Full-Length MS Protein Standard

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Product Description


NameCUL4B Full-Length MS Protein Standard
Cat#CPFL306935
Protein Namecullin 4B
SymbolCUL4B
SynonymsCUL-4B; MRXHF2; MRXS15; MRXSC; SFM2
AccessionNM_003588
CytogeneticXq23
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionCUL4B Full-Length MS Protein Standard (NP_003579), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene is a member of the cullin family. The encoded protein forms a complex that functions as an E3 ubiquitin ligase and catalyzes the polyubiquitination of specific protein substrates in the cell. The protein interacts with a ring finger protein, and is required for the proteolysis of several regulators of DNA replication including chromatin licensing and DNA replication factor 1 and cyclin E. Multiple transcript variants encoding different isoforms have been found for this gene.

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