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HPD Full-Length MS Protein Standard

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Product Description


NameHPD Full-Length MS Protein Standard
Cat#CPFL306860
Protein Name4-hydroxyphenylpyruvate dioxygenase
SymbolHPD
Synonyms4-HPPD; 4HPPD; GLOD3; HPPDASE; PPD
AccessionNM_002150
Cytogenetic12q24.31
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionHPD Full-Length MS Protein Standard (NP_002141), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. The protein encoded by this gene is an enzyme in the catabolic pathway of tyrosine. The encoded protein catalyzes the conversion of 4-hydroxyphenylpyruvate to homogentisate. Defects in this gene are a cause of tyrosinemia type 3 (TYRO3) and hawkinsinuria (HAWK). Two transcript variants encoding different isoforms have been found for this gene.

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