NPTX2 Full-Length MS Protein Standard


Product Description:

Name NPTX2 Full-Length MS Protein Standard
Cat# CPFL306713
Protein Nameneuronal pentraxin II
SymbolNPTX2
SynonymsNARP; NP-II; NP2
AccessionNM_002523
Cytogenetic7q21.3-q22.1
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW46.9 kDa
Expression TrueORF CloneRC206713
DescriptionNPTX2 Full-Length MS Protein Standard (NP_002514), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes a member of the family of neuronal petraxins, synaptic proteins that are related to C-reactive protein. This protein is involved in excitatory synapse formation. It also plays a role in clustering of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)-type glutamate receptors at established synapses, resulting in non-apoptotic cell death of dopaminergic nerve cells. Up-regulation of this gene in Parkinson disease (PD) tissues suggests that the protein may be involved in the pathology of PD.

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