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LDLRAP1 Full-Length MS Protein Standard


Product Description

NameLDLRAP1 Full-Length MS Protein Standard
Protein Namelow density lipoprotein receptor adaptor protein 1
SynonymsARH; ARH1; ARH2; FHCB1; FHCB2
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionLDLRAP1 Full-Length MS Protein Standard (NP_056442), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. The protein encoded by this gene is a cytosolic protein which contains a phosphotyrosine binding (PTD) domain. The PTD domain has been found to interact with the cytoplasmic tail of the LDL receptor. Mutations in this gene lead to LDL receptor malfunction and cause the disorder autosomal recessive hypercholesterolaemia.

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