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HSD3B2 Full-Length MS Protein Standard

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Product Description


NameHSD3B2 Full-Length MS Protein Standard
Cat#CPFL306593
Protein Namehydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2
SymbolHSD3B2
SynonymsHSD3B; HSDB; SDR11E2
AccessionNM_000198
Cytogenetic1p13.1
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionHSD3B2 Full-Length MS Protein Standard (NP_000189), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. The protein encoded by this gene is a bifunctional enzyme that catalyzes the oxidative conversion of delta(5)-ene-3-beta-hydroxy steroid, and the oxidative conversion of ketosteroids. It plays a crucial role in the biosynthesis of all classes of hormonal steroids. This gene is predominantly expressed in the adrenals and the gonads. Mutations in this gene are associated with 3-beta-hydroxysteroid dehydrogenase, type II, deficiency. Alternatively spliced transcript variants have been found for this gene.

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