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PDE1B Full-Length MS Protein Standard

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Product Description


NamePDE1B Full-Length MS Protein Standard
Cat#CPFL306588
Protein Namephosphodiesterase 1B, calmodulin-dependent
SymbolPDE1B
SynonymsPDE1B1; PDES1B
AccessionNM_000924
Cytogenetic12q13
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionPDE1B Full-Length MS Protein Standard (NP_000915), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. The protein encoded by this gene belongs to the cyclic nucleotide phosphodiesterase (PDE) family, and PDE1 subfamily. Members of the PDE1 family are calmodulin-dependent PDEs that are stimulated by a calcium-calmodulin complex. This PDE has dual-specificity for the second messengers, cAMP and cGMP, with a preference for cGMP as a substrate. cAMP and cGMP function as key regulators of many important physiological processes. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

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