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CD247 Full-Length MS Protein Standard

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Product Description


NameCD247 Full-Length MS Protein Standard
Cat#CPFL306562
Protein NameCD247 Molecule
SymbolCD247
SynonymsCD3-ZETA; CD3H; CD3Q; CD3Z; IMD25; T3Z; TCRZ
AccessionNM_000734
Cytogenetic1q24.2
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionCD247 Full-Length MS Protein Standard (NP_000725), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. The protein encoded by this gene is T-cell receptor zeta, which together with T-cell receptor alpha/beta and gamma/delta heterodimers, and with CD3-gamma, -delta and -epsilon, forms the T-cell receptor-CD3 complex. The zeta chain plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. Low expression of the antigen results in impaired immune response. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

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