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MYOC Full-Length MS Protein Standard

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Product Description


NameMYOC Full-Length MS Protein Standard
Cat#CPFL306556
Protein Namemyocilin, trabecular meshwork inducible glucocorticoid response
SymbolMYOC
SynonymsGLC1A; GPOA; JOAG; JOAG1; myocilin; TIGR
AccessionNM_000261
Cytogenetic1q23-q24
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionMYOC Full-Length MS Protein Standard (NP_000252), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. MYOC encodes the protein myocilin, which is believed to have a role in cytoskeletal function. MYOC is expressed in many occular tissues, including the trabecular meshwork, and was revealed to be the trabecular meshwork glucocorticoid-inducible response protein (TIGR). The trabecular meshwork is a specialized eye tissue essential in regulating intraocular pressure, and mutations in MYOC have been identified as the cause of hereditary juvenile-onset open-angle glaucoma.

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