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IGFALS Full-Length MS Protein Standard

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Product Description


NameIGFALS Full-Length MS Protein Standard
Cat#CPFL306542
Protein Nameinsulin-like growth factor binding protein, acid labile subunit
SymbolIGFALS
SynonymsACLSD; ALS
AccessionNM_004970
Cytogenetic16p13.3
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionIGFALS Full-Length MS Protein Standard (NP_004961), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. The protein encoded by this gene is a serum protein that binds insulin-like growth factors, increasing their half-life and their vascular localization. Production of the encoded protein, which contains twenty leucine-rich repeats, is stimulated by growth hormone. Defects in this gene are a cause of acid-labile subunit deficiency, which maifests itself in a delayed and slow puberty. Three transcript variants encoding two different isoforms have been found for this gene.

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