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CD177 Full-Length MS Protein Standard

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Product Description


NameCD177 Full-Length MS Protein Standard
Cat#CPFL306463
Protein NameCD177 Molecule
SymbolCD177
SynonymsHNA-2a; HNA2A; NB1; NB1 GP; PRV-1; PRV1
AccessionNM_020406
Cytogenetic19q13.2
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionCD177 Full-Length MS Protein Standard (NP_065139), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes a glycosyl-phosphatidylinositol (GPI)-linked cell surface glycoprotein that plays a role in neutrophil activation. The protein can bind platelet endothelial cell adhesion molecule-1 and function in neutrophil transmigration. Mutations in this gene are associated with myeloproliferative diseases. Over-expression of this gene has been found in patients with polycythemia rubra vera. Autoantibodies against the protein may result in pulmonary transfusion reactions, and it may be involved in Wegeners granulomatosis. A related pseudogene, which is adjacent to this gene on chromosome 19, has been identified.

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