GLS Full-Length MS Protein Standard


Product Description:

Name GLS Full-Length MS Protein Standard
Cat# CPFL306265
Protein NameGls glutaminase
SymbolGLS
SynonymsAAD20; GAC; GAM; GLS1; KGA
AccessionNM_014905
Cytogenetic2q32-q34
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW73.3 kDa
Expression TrueORF CloneRC206265
DescriptionGLS Full-Length MS Protein Standard (NP_055720), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes the K-type mitochondrial glutaminase. The encoded protein is an phosphate-activated amidohydrolase that catalyzes the hydrolysis of glutamine to glutamate and ammonia. This protein is primarily expressed in the brain and kidney plays an essential role in generating energy for metabolism, synthesizing the brain neurotransmitter glutamate and maintaining acid-base balance in the kidney. Alternate splicing results in multiple transcript variants.

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