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RASSF8 Full-Length MS Protein Standard

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Product Description


NameRASSF8 Full-Length MS Protein Standard
Cat#CPFL306104
Protein NameRas association (RalGDS/AF-6) domain family (N-terminal) member 8
SymbolRASSF8
SynonymsC12orf2; HOJ1
AccessionNM_007211
Cytogenetic12p12.3
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionRASSF8 Full-Length MS Protein Standard (NP_009142), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes a member of the Ras-assocation domain family (RASSF) of tumor suppressor proteins. This gene is essential for maintaining adherens junction function in epithelial cells and has a role in epithelial cell migration. It is a lung tumor suppressor gene candidate. A chromosomal translocation t(12;22)(p11.2;q13.3) leading to the fusion of this gene and the FBLN1 gene is found in a complex type of synpolydactyly. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

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