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THAP1 Full-Length MS Protein Standard

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Product Description


NameTHAP1 Full-Length MS Protein Standard
Cat#CPFL306000
Protein NameTHAP domain containing, apoptosis associated protein 1
SymbolTHAP1
SynonymsDYT6
AccessionNM_018105
Cytogenetic8p11.21
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionTHAP1 Full-Length MS Protein Standard (NP_060575), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. The protein encoded by this gene contains a THAP domain, a conserved DNA-binding domain. This protein colocalizes with the apoptosis response protein PAWR/PAR-4 in promyelocytic leukemia (PML) nuclear bodies, and functions as a proapoptotic factor that links PAWR to PML nuclear bodies. Alternatively spliced transcript variants encoding distinct isoforms have been observed.

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