ATG4C Full-Length MS Protein Standard


Product Description:

Name ATG4C Full-Length MS Protein Standard
Cat# CPFL305955
Protein NameATG4 autophagy related 4 homolog C
SymbolATG4C
SynonymsAPG4-C; APG4C; AUTL1; AUTL3
AccessionNM_178221
Cytogenetic1p31.3
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW52.3 kDa
Expression TrueORF CloneRC205955
DescriptionATG4C Full-Length MS Protein Standard (NP_835739), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Alternate transcriptional splice variants, encoding the same protein, have been characterized.

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