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MAP4K5 Full-Length MS Protein Standard

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Product Description


NameMAP4K5 Full-Length MS Protein Standard
Cat#CPFL305952
Protein Namemitogen-activated protein kinase kinase kinase kinase 5
SymbolMAP4K5
SynonymsGCKR; KHS; KHS1; MAPKKKK5
AccessionNM_198794
Cytogenetic14q11.2-q21
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionMAP4K5 Full-Length MS Protein Standard (NP_942089), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes a member of the serine/threonine protein kinase family, that is highly similar to yeast SPS1/STE20 kinase. Yeast SPS1/STE20 functions near the beginning of the MAP kinase signal cascades that is essential for yeast pheromone response. This kinase was shown to activate Jun kinase in mammalian cells, which suggested a role in stress response. Two alternatively spliced transcript variants encoding the same protein have been described for this gene.

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