PDK2 Full-Length MS Protein Standard


Product Description:

Name PDK2 Full-Length MS Protein Standard
Cat# CPFL305937
Protein Namepyruvate dehydrogenase kinase, isozyme 2
SymbolPDK2
SynonymsPDHK2; PDKII
AccessionNM_002611
Cytogenetic17q21.33
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW46 kDa
Expression TrueORF CloneRC205937
DescriptionPDK2 Full-Length MS Protein Standard (NP_002602), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes a member of the pyruvate dehydrogenase kinase family. The encoded protein phosphorylates pyruvate dehydrogenase, down-regulating the activity of the mitochondrial pyruvate dehydrogenase complex. Overexpression of this gene may play a role in both cancer and diabetes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

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