BIRC5 Full-Length MS Protein Standard


Product Description:

Name BIRC5 Full-Length MS Protein Standard
Cat# CPFL305935
Protein Namebaculoviral IAP repeat containing 5
SymbolBIRC5
SynonymsAPI4; EPR-1
AccessionNM_001168
Cytogenetic17q25
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW16.2 kDa
Expression TrueORF CloneRC205935
DescriptionBIRC5/Survivin Full-Length MS Protein Standard (NP_001159), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene is a member of the inhibitor of apoptosis (IAP) gene family, which encode negative regulatory proteins that prevent apoptotic cell death. IAP family members usually contain multiple baculovirus IAP repeat (BIR) domains, but this gene encodes proteins with only a single BIR domain. The encoded proteins also lack a C-terminus RING finger domain. Gene expression is high during fetal development and in most tumors, yet low in adult tissues. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

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