BUB1B Full-Length MS Protein Standard


Product Description:

Name BUB1B Full-Length MS Protein Standard
Cat# CPFL305844
Protein Namebudding uninhibited by benzimidazoles 1 homolog beta
SymbolBUB1B
SynonymsBub1A; BUB1beta; BUBR1; hBUBR1; MAD3L; MVA1; SSK1
AccessionNM_001211
Cytogenetic15q15
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW119.3 kDa
Expression TrueORF CloneRC205844
DescriptionBUB1B Full-Length MS Protein Standard (NP_001202), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes a kinase involved in spindle checkpoint function. The protein has been localized to the kinetochore and plays a role in the inhibition of the anaphase-promoting complex/cyclosome (APC/C), delaying the onset of anaphase and ensuring proper chromosome segregation. Impaired spindle checkpoint function has been found in many forms of cancer.

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