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NPLOC4 Full-Length MS Protein Standard

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Product Description


NameNPLOC4 Full-Length MS Protein Standard
Cat#CPFL305829
Protein Namenuclear protein localization 4 homolog (S. cerevisiae)
SymbolNPLOC4
SynonymsNPL4
AccessionNM_017921
Cytogenetic17qter
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionNPLOC4 Full-Length MS Protein Standard (NP_060391), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. The ternary complex containing UFD1L, VCP and NPLOC4 binds ubiquitinated proteins and is necessary for the export of misfolded proteins from the ER to the cytoplasm, where they are degraded by the proteasome. The NPLOC4-UFD1L-VCP complex regulates spindle disassembly at the end of mitosis and is necessary for the formation of a closed nuclear envelope.

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