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ASPSCR1 Full-Length MS Protein Standard

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Product Description


NameASPSCR1 Full-Length MS Protein Standard
Cat#CPFL305817
Protein Namealveolar soft part sarcoma chromosome region, candidate 1
SymbolASPSCR1
SynonymsASPCR1; ASPL; ASPS; RCC17; TUG; UBXD9; UBXN9
AccessionNM_024083
Cytogenetic17q25.3
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionASPSCR1 Full-Length MS Protein Standard (NP_076988), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. The protein encoded by this gene contains a UBX domain and interacts with glucose transporter type 4 (GLUT4). This protein is a tether, which sequesters the GLUT4 in intracellular vesicles in muscle and fat cells in the absence of insulin, and redistributes the GLUT4 to the plasma membrane within minutes of insulin stimulation. Translocation t(X;17)(p11;q25) of this gene with transcription factor TFE3 gene results in a ASPSCR1-TFE3 fusion protein in alveolar soft part sarcoma and in renal cell carcinomas. Multiple alternatively spliced transcript variants have been found.

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