CACNG6 Full-Length MS Protein Standard


Product Description:

Name CACNG6 Full-Length MS Protein Standard
Cat# CPFL305809
Protein Namecalcium channel, voltage-dependent, gamma subunit 6
SymbolCACNG6
Synonyms2310033H20Rik; AW050150; MGC144251; MGC144252; voltage-dependent calcium channel gamma-6 subunit; calcium channel, voltage-dependent, gamma subunit 6
AccessionNM_145814
Cytogenetic19q13.4
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW27.9 kDa
Expression TrueORF CloneRC205809
DescriptionCACNG6 Full-Length MS Protein Standard (NP_665813), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. Voltage-dependent calcium channels are composed of five subunits. The protein encoded by this gene represents one of these subunits, gamma, and is one of two known gamma subunit proteins. This particular gamma subunit is an integral membrane protein that is thought to stabilize the calcium channel in an inactive (closed) state. This gene is part of a functionally diverse eight-member protein subfamily of the PMP-22/EMP/MP20 family and is located in a cluster with two family members that function as transmembrane AMPA receptor regulatory proteins (TARPs). Alternative splicing results in multiple transcript variants. Variants in this gene have been associated with aspirin-intolerant asthma.

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