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FBLIM1 Full-Length MS Protein Standard

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Product Description


NameFBLIM1 Full-Length MS Protein Standard
Cat#CPFL305764
Protein Namefilamin binding LIM protein 1
SymbolFBLIM1
SynonymsCAL; FBLP-1; FBLP1
AccessionNM_017556
Cytogenetic1p36.21
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionFBLIM1 Full-Length MS Protein Standard (NP_060026), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes a protein with an N-terminal filamin-binding domain, a central proline-rich domain, and, multiple C-terminal LIM domains. This protein localizes at cell junctions and may link cell adhesion structures to the actin cytoskeleton. This protein may be involved in the assembly and stabilization of actin-filaments and likely plays a role in modulating cell adhesion, cell morphology and cell motility. This protein also localizes to the nucleus and may affect cardiomyocyte differentiation after binding with the CSX/NKX2-5 transcription factor. Alternative splicing results in multiple transcript variants encoding different isoforms.

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