Home > Products > Stable Isotope Labeled Full Length MS Protein Standard > DR1 Full-Length MS Protein Standard

DR1 Full-Length MS Protein Standard

INQUIRY>

Product Description


NameDR1 Full-Length MS Protein Standard
Cat#CPFL305733
Protein Namedown-regulator of transcription 1, TBP-binding (negative cofactor 2)
SymbolDR1
SynonymsNC2; NC2-BETA
AccessionNM_001938
Cytogenetic1p22.1
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionDR1 Full-Length MS Protein Standard (NP_001929), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes a TBP- (TATA box-binding protein) associated phosphoprotein that represses both basal and activated levels of transcription. The encoded protein is phosphorylated in vivo and this phosphorylation affects its interaction with TBP. This protein contains a histone fold motif at the amino terminus, a TBP-binding domain, and a glutamine- and alanine-rich region. The binding of DR1 repressor complexes to TBP-promoter complexes may establish a mechanism in which an altered DNA conformation, together with the formation of higher order complexes, inhibits the assembly of the preinitiation complex and controls the rate of RNA polymerase II transcription.

Products List:

Cat#Protein SequencePrice

If the product of interest is not available in our catalog, we can synthesize for you with our quality controlled
Customized Synthesized Peptide/Proteins Service!

Online Inquiry


Please input "proteomics" as verification code.