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KIN Full-Length MS Protein Standard

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Product Description


NameKIN Full-Length MS Protein Standard
Cat#CPFL305689
Protein NameKIN, antigenic determinant of recA protein homolog (mouse)
SymbolKIN
SynonymsBTCD; KIN17; Rts2
AccessionNM_012311
Cytogenetic10p15-p14
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionKIN Full-Length MS Protein Standard (NP_036443), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. The protein encoded by this gene is a nuclear protein that forms intranuclear foci during proliferation and is redistributed in the nucleoplasm during the cell cycle. Short-wave ultraviolet light provokes the relocalization of the protein, suggesting its participation in the cellular response to DNA damage. Originally selected based on protein-binding with RecA antibodies, the mouse protein presents a limited similarity with a functional domain of the bacterial RecA protein, a characteristic shared by this human ortholog. Alternative splicing of this gene results in multiple transcript variants.

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