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GPSM2 Full-Length MS Protein Standard

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Product Description


NameGPSM2 Full-Length MS Protein Standard
Cat#CPFL305650
Protein NameG-protein signaling modulator 2
SymbolGPSM2
SynonymsCMCS; DFNB82; LGN; PINS
AccessionNM_013296
Cytogenetic1p13.3
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionGPSM2 Full-Length MS Protein Standard (NP_037428), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. The protein encoded by this gene belongs to a family of proteins that modulate activation of G proteins, which transduce extracellular signals received by cell surface receptors into integrated cellular responses. The N-terminal half of this protein contains 10 copies of leu-gly-asn (LGN) repeat, and the C-terminal half contains 4 GoLoco motifs, which are involved in guanine nucleotide exchange. This protein may play a role in neuroblast division and in the development of normal hearing. Mutations in this gene are associated with autosomal recessive nonsyndromic deafness (DFNB82).

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