EIF4A2 Full-Length MS Protein Standard


Product Description:

Name EIF4A2 Full-Length MS Protein Standard
Cat# CPFL305623
Protein Nameeukaryotic translation initiation factor 4A2
SymbolEIF4A2
SynonymsBM-010; DDX2B; eIF-4A-II; EIF4A; eIF4A-II; EIF4F
AccessionNM_001967
Cytogenetic3q28
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW46.2 kDa
Expression TrueORF CloneRC205623
DescriptionEIF4A2 Full-Length MS Protein Standard (NP_001958), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. ATP-dependent RNA helicase which is a subunit of the eIF4F complex involved in cap recognition and is required for mRNA binding to ribosome. In the current model of translation initiation, eIF4A unwinds RNA secondary structures in the 5-UTR of mRNAs which is necessary to allow efficient binding of the small ribosomal subunit, and subsequent scanning for the initiator codon.

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