SAP18 Full-Length MS Protein Standard


Product Description:

Name SAP18 Full-Length MS Protein Standard
Cat# CPFL305607
Protein NameSin3A-associated protein, 18kDa
SymbolSAP18
Synonyms2HOR0202; SAP18P
AccessionNM_005870
Cytogenetic13q12.11
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW17.4 kDa
Expression TrueORF CloneRC205607
DescriptionSAP18 Full-Length MS Protein Standard (NP_005861), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. Histone acetylation plays a key role in the regulation of eukaryotic gene expression. Histone acetylation and deacetylation are catalyzed by multisubunit complexes. The protein encoded by this gene is a component of the histone deacetylase complex, which includes SIN3, SAP30, HDAC1, HDAC2, RbAp46, RbAp48, and other polypeptides. This protein directly interacts with SIN3 and enhances SIN3-mediated transcriptional repression when tethered to the promoter. A pseudogene has been identified on chromosome 2.

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