ZCRB1 Full-Length MS Protein Standard


Product Description:

Name ZCRB1 Full-Length MS Protein Standard
Cat# CPFL305492
Protein Namezinc finger CCHC-type and RNA binding motif 1
SymbolZCRB1
SynonymsMADP-1; MADP1; RBM36; SNRNP31; ZCCHC19
AccessionNM_033114
Cytogenetic12q12
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW24.4 kDa
Expression TrueORF CloneRC205492
DescriptionZCRB1 Full-Length MS Protein Standard (NP_149105), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. Pre-mRNA splicing is catalyzed by the spliceosome. U12-type spliceosome binds U12-type pre-mRNAs and recognizes the 5 splice site and branch-point sequence. U11 and U12 snRNPs are components of U12-type spliceosome and function as a molecular bridge connecting both ends of the intron. The protein encoded by this gene contains a RNA recognition motif. It was identified as one of the protein components of U11/U12 snRNPs. This protein and many other U11/U12 snRNP proteins are highly conserved in organisms known to contain U12-type introns. These proteins have been shown to be essential for cell viability, suggesting the key roles in U12-type splicing.

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