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MARCH8 Full-Length MS Protein Standard

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Product Description


NameMARCH8 Full-Length MS Protein Standard
Cat#CPFL305477
Protein Namemembrane-associated ring finger (C3HC4) 8, E3 ubiquitin protein ligase
SymbolMARCH8
Synonymsc-MIR; CMIR; MARCH-VIII; MIR; RNF178
AccessionNM_001002266
Cytogenetic10q11.21
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionMARCH8 Full-Length MS Protein Standard (NP_001002266), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. MARCH8 is a member of the MARCH family of membrane-bound E3 ubiquitin ligases (EC 6.3.2.19). MARCH enzymes add ubiquitin (see MIM 191339) to target lysines in substrate proteins, thereby signaling their vesicular transport between membrane compartments. MARCH8 induces the internalization of several membrane glycoproteins (Goto et al., 2003 )

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