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KPNA4 Full-Length MS Protein Standard

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Product Description


NameKPNA4 Full-Length MS Protein Standard
Cat#CPFL305448
Protein Namekaryopherin alpha 4 (importin alpha 3)
SymbolKPNA4
SynonymsIPOA3; QIP1; SRP3
AccessionNM_002268
Cytogenetic3q25.33
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionKPNA4 Full-Length MS Protein Standard (NP_002259), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. The nuclear import of karyophilic proteins is directed by short amino acid sequences termed nuclear localization signals (NLSs). Karyopherins, or importins, are cytoplasmic proteins that recognize NLSs and dock NLS-containing proteins to the nuclear pore complex. The protein encoded by this gene shares the sequence similarity with Xenopus importin-alpha and Saccharomyces cerevisiae Srp1. This protein is found to interact with the NLSs of DNA helicase Q1 and SV40 T antigen.

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