KPNA4 Full-Length MS Protein Standard


Product Description:

Name KPNA4 Full-Length MS Protein Standard
Cat# CPFL305448
Protein Namekaryopherin alpha 4 (importin alpha 3)
SymbolKPNA4
SynonymsIPOA3; QIP1; SRP3
AccessionNM_002268
Cytogenetic3q25.33
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW57.7 kDa
Expression TrueORF CloneRC205448
DescriptionKPNA4 Full-Length MS Protein Standard (NP_002259), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. The nuclear import of karyophilic proteins is directed by short amino acid sequences termed nuclear localization signals (NLSs). Karyopherins, or importins, are cytoplasmic proteins that recognize NLSs and dock NLS-containing proteins to the nuclear pore complex. The protein encoded by this gene shares the sequence similarity with Xenopus importin-alpha and Saccharomyces cerevisiae Srp1. This protein is found to interact with the NLSs of DNA helicase Q1 and SV40 T antigen.

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