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LMO2 Full-Length MS Protein Standard

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Product Description


NameLMO2 Full-Length MS Protein Standard
Cat#CPFL305376
Protein NameLIM domain only 2 (rhombotin-like 1)
SymbolLMO2
SynonymsRBTN2; RBTNL1; RHOM2; TTG2
AccessionNM_005574
Cytogenetic11p13
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionLMO2 Full-Length MS Protein Standard (NP_005565), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. LMO2 encodes a cysteine-rich, two LIM-domain protein that is required for yolk sac erythropoiesis. The LMO2 protein has a central and crucial role in hematopoietic development and is highly conserved. The LMO2 transcription start site is located approximately 25 kb downstream from the 11p13 T-cell translocation cluster (11p13 ttc), where a number T-cell acute lymphoblastic leukemia-specific translocations occur. Alternative splicing results in multiple transcript variants encoding different isoforms.

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