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BIRC2 Full-Length MS Protein Standard


Product Description

NameBIRC2 Full-Length MS Protein Standard
Protein Namebaculoviral IAP repeat containing 2
SynonymsAPI1; c-IAP1; cIAP1; Hiap-2; HIAP2; MIHB; RNF48
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionBIRC2 Full-Length MS Protein Standard (NP_001157), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. The protein encoded by this gene is a member of a family of proteins that inhibits apoptosis by binding to tumor necrosis factor receptor-associated factors TRAF1 and TRAF2, probably by interfering with activation of ICE-like proteases. This encoded protein inhibits apoptosis induced by serum deprivation and menadione, a potent inducer of free radicals. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

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