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ACSL4 Full-Length MS Protein Standard

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Product Description


NameACSL4 Full-Length MS Protein Standard
Cat#CPFL305356
Protein Nameacyl-CoA synthetase long-chain family member 4
SymbolACSL4
SynonymsACS4; FACL4; LACS4; MRX63; MRX68
AccessionNM_004458
CytogeneticXq22.3-q23
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionACSL4 Full-Length MS Protein Standard (NP_004449), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. This isozyme preferentially utilizes arachidonate as substrate. The absence of this enzyme may contribute to the mental retardation or Alport syndrome. Alternative splicing of this gene generates 2 transcript variants.

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