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VPS26A Full-Length MS Protein Standard

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Product Description


NameVPS26A Full-Length MS Protein Standard
Cat#CPFL305353
Protein Namevacuolar protein sorting 26 homolog A (S. pombe)
SymbolVPS26A
SynonymsHB58; Hbeta58; PEP8A; VPS26
AccessionNM_004896
Cytogenetic10q21.1
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionVPS26A Full-Length MS Protein Standard (NP_004887), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene belongs to a group of vacuolar protein sorting (VPS) genes. The encoded protein is a component of a large multimeric complex, termed the retromer complex, involved in retrograde transport of proteins from endosomes to the trans-Golgi network. The close structural similarity between the yeast and human proteins that make up this complex suggests a similarity in function. Expression studies in yeast and mammalian cells indicate that this protein interacts directly with VPS35, which serves as the core of the retromer complex. Alternative splicing results in multiple transcript variants encoding different isoforms.

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