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ALDH1A2 Full-Length MS Protein Standard

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Product Description


NameALDH1A2 Full-Length MS Protein Standard
Cat#CPFL305342
Protein Namealdehyde dehydrogenase 1 family, member A2
SymbolALDH1A2
SynonymsRALDH(II); RALDH2; RALDH2-T
AccessionNM_170696
Cytogenetic15q21.3
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionALDH1A2 Full-Length MS Protein Standard (NP_733797), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This protein belongs to the aldehyde dehydrogenase family of proteins. The product of this gene is an enzyme that catalyzes the synthesis of retinoic acid (RA) from retinaldehyde. Retinoic acid, the active derivative of vitamin A (retinol), is a hormonal signaling molecule that functions in developing and adult tissues. The studies of a similar mouse gene suggest that this enzyme and the cytochrome CYP26A1, concurrently establish local embryonic retinoic acid levels which facilitate posterior organ development and prevent spina bifida. Four transcript variants encoding distinct isoforms have been identified for this gene.

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