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MAGEB2 Full-Length MS Protein Standard

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Product Description


NameMAGEB2 Full-Length MS Protein Standard
Cat#CPFL305338
Protein Namemelanoma antigen family B, 2
SymbolMAGEB2
SynonymsCT3.2; DAM6; MAGE-XP-2
AccessionNM_002364
CytogeneticXp21.3
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionMAGEB2 Full-Length MS Protein Standard (NP_002355), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene is a member of the MAGEB gene family. The members of this family have their entire coding sequences located in the last exon, and the encoded proteins show 50 to 68% sequence identity to each other. The promoters and first exons of the MAGEB genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. This gene is localized in the DSS (dosage-sensitive sex reversal) critical region. It is expressed in testis and placenta, and in a significant fraction of tumors of various histological types. The MAGEB genes are clustered on chromosome Xp22-p21.

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