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PDE1A Full-Length MS Protein Standard

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Product Description


NamePDE1A Full-Length MS Protein Standard
Cat#CPFL305292
Protein NamePDE1A phosphodiesterase 1A, calmodulin-dependent
SymbolPDE1A
SynonymsCAM-PDE-1A; HCAM-1; HCAM1; HSPDE1A
AccessionNM_005019
Cytogenetic2q32.1
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionPDE1A Full-Length MS Protein Standard (NP_005010), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. Cyclic nucleotide phosphodiesterases (PDEs) play a role in signal transduction by regulating intracellular cyclic nucleotide concentrations through hydrolysis of cAMP and/or cGMP to their respective nucleoside 5-prime monophosphates. Members of the PDE1 family, such as PDE1A, are Ca(2+)/calmodulin (see CALM1; MIM 114180)-dependent PDEs (CaM-PDEs) that are activated by calmodulin in the presence of Ca(2+) (Michibata et al., 2001 )

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