CRHBP Full-Length MS Protein Standard


Product Description:

Name CRHBP Full-Length MS Protein Standard
Cat# CPFL305258
Protein Namecorticotropin releasing hormone binding protein
SymbolCRHBP
SynonymsCRF-BP; CRFBP
AccessionNM_001882
Cytogenetic5q11.2-q13.3
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW36 kDa
Expression TrueORF CloneRC205258
DescriptionCRHBP Full-Length MS Protein Standard (NP_001873), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. Corticotropin-releasing hormone is a potent stimulator of synthesis and secretion of preopiomelanocortin-derived peptides. Although CRH concentrations in the human peripheral circulation are normally low, they increase throughout pregnancy and fall rapidly after parturition. Maternal plasma CRH probably originates from the placenta. Human plasma contains a CRH-binding protein which inactivates CRH and which may prevent inappropriate pituitary-adrenal stimulation in pregnancy.

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