TBK1 Full-Length MS Protein Standard


Product Description:

Name TBK1 Full-Length MS Protein Standard
Cat# CPFL305238
Protein NameTANK-binding kinase 1
SymbolTBK1
SynonymsNAK; T2K
AccessionNM_013254
Cytogenetic12q14.1
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW83.5 kDa
Expression TrueORF CloneRC205238
DescriptionTBK1 Full-Length MS Protein Standard (NP_037386), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. The NF-kappa-B (NFKB) complex of proteins is inhibited by I-kappa-B (IKB) proteins, which inactivate NFKB by trapping it in the cytoplasm. Phosphorylation of serine residues on the IKB proteins by IKB kinases marks them for destruction via the ubiquitination pathway, thereby allowing activation and nuclear translocation of the NFKB complex. The protein encoded by this gene is similar to IKB kinases and can mediate NFKB activation in response to certain growth factors.

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