FGD1 Full-Length MS Protein Standard


Product Description:

Name FGD1 Full-Length MS Protein Standard
Cat# CPFL305133
Protein NameFYVE, RhoGEF and PH domain containing 1
SymbolFGD1
SynonymsAAS; FGDY; MRXS16; ZFYVE3
AccessionNM_004463
CytogeneticXp11.21
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW106.4 kDa
Expression TrueORF CloneRC205133
DescriptionFGD1 Full-Length MS Protein Standard (NP_004454), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes a protein that contains Dbl (DH) and pleckstrin (PH) homology domains and is similar to the Rho family of small GTP-binding proteins. The encoded protein specifically binds to the Rho family GTPase Cdc42Hs and can stimulate the GDP-GTP exchange of the isoprenylated form of Cdc42Hs. It also stimulates the mitogen activated protein kinase cascade leading to c-Jun kinase SAPK/JNK1 activation. Defects in this gene are the cause of faciogenital dysplasia and X-linked mental retardation, syndromatic 16.

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