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CFL2 Full-Length MS Protein Standard

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Product Description


NameCFL2 Full-Length MS Protein Standard
Cat#CPFL305105
Protein Namecofilin 2 (muscle)
SymbolCFL2
SynonymsNEM7
AccessionNM_021914
Cytogenetic14q12
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionCFL2 Full-Length MS Protein Standard (NP_068733), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes an intracellular protein that is involved in the regulation of actin-filament dynamics. This protein is a major component of intranuclear and cytoplasmic actin rods. It can bind G- and F-actin in a 1:1 ratio of cofilin to actin, and it reversibly controls actin polymerization and depolymerization in a pH-dependent manner. Mutations in this gene cause nemaline myopathy type 7, a form of congenital myopathy. Alternative splicing results in multiple transcript variants.

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