TWIST2 Full-Length MS Protein Standard


Product Description:

Name TWIST2 Full-Length MS Protein Standard
Cat# CPFL305006
Protein Nametwist family bHLH transcription factor 2
SymbolTWIST2
SynonymsbHLHa39; DERMO1; FFDD3; SETLSS
AccessionNM_057179
Cytogenetic2q37.3
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW17.9 kDa
Expression TrueORF CloneRC205006
DescriptionTWIST2 Full-Length MS Protein Standard (NP_476527), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. The protein encoded by this gene is a basic helix-loop-helix type transcription factor and shares similarity with Twist. This protein may inhibit osteoblast maturation and maintain cells in a preosteoblast phenotype during osteoblast development. This gene may be upregulated in certain cancers. Mutations in this gene cause focal facial dermal dysplasia 3, Setleis type. Two transcript variants encoding the same protein have been found.

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