CDC42EP2 Full-Length MS Protein Standard


Product Description:

Name CDC42EP2 Full-Length MS Protein Standard
Cat# CPFL304974
Protein NameCDC42 effector protein (Rho GTPase binding) 2
SymbolCDC42EP2
SynonymsBORG1; CEP2
AccessionNM_006779
Cytogenetic11q13
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW22.3 kDa
Expression TrueORF CloneRC204974
DescriptionCDC42EP2 Full-Length MS Protein Standard (NP_006770), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. CDC42, a small Rho GTPase, regulates the formation of F-actin-containing structures through its interaction with the downstream effector proteins. The protein encoded by this gene is a member of the Borg family of CDC42 effector proteins. Borg family proteins contain a CRIB (Cdc42/Rac interactive-binding) domain. They bind to, and negatively regulate the function of CDC42. Coexpression of this protein with CDC42 suggested a role of this protein in actin filament assembly and cell shape control.

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