TBC1D20 Full-Length MS Protein Standard


Product Description:

Name TBC1D20 Full-Length MS Protein Standard
Cat# CPFL304927
Protein NameTBC1 domain family, member 20
SymbolTBC1D20
SynonymsC20orf140; WARBM4
AccessionNM_144628
Cytogenetic20p13
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW45.7 kDa
Expression TrueORF CloneRC204927
DescriptionTBC1D20 Full-Length MS Protein Standard (NP_653229), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes a protein that belongs to a family of GTPase activator proteins of Rab-like small GTPases. The encoded protein and its cognate GTPase, Rab1, bind the nonstructural protein 5A (NS5A) of the hepatitis C virus (HCV) to mediate viral replication. Depletion of this protein inhibits replication of the virus and HCV infection. Mutations in this gene are associated with Warburg micro syndrome 4. Alternative splicing results in multiple transcript variants.

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