BIRC7 Full-Length MS Protein Standard


Product Description:

Name BIRC7 Full-Length MS Protein Standard
Cat# CPFL304906
Protein Namebaculoviral IAP repeat containing 7
SymbolBIRC7
SynonymsKIAP; LIVIN; ML-IAP; MLIAP; RNF50
AccessionNM_139317
Cytogenetic20q13.3
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW32.6 kDa
Expression TrueORF CloneRC204906
DescriptionBIRC7 Full-Length MS Protein Standard (NP_647478), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes a member of the inhibitor of apoptosis protein (IAP) family, and contains a single copy of a baculovirus IAP repeat (BIR) as well as a RING-type zinc finger domain. The BIR domain is essential for inhibitory activity and interacts with caspases, while the RING finger domain sometimes enhances antiapoptotic activity but does not inhibit apoptosis alone. Elevated levels of the encoded protein may be associated with cancer progression and play a role in chemotherapy sensitivity. Alternative splicing results in multiple transcript variants )

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