| Name | ALDH4A1 Full-Length MS Protein Standard |
|---|---|
| Cat# | CPFL304884 |
| Protein Name | aldehyde dehydrogenase 4 family, member A1 |
| Symbol | ALDH4A1 |
| Synonyms | ALDH4; P5CD; P5CDh |
| Accession | NM_170726 |
| Cytogenetic | 1p36 |
| Amino Acid Labeled | [U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys |
| Description | ALDH4A1 Full-Length MS Protein Standard (NP_733844), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This protein belongs to the aldehyde dehydrogenase family of proteins. This enzyme is a mitochondrial matrix NAD-dependent dehydrogenase which catalyzes the second step of the proline degradation pathway, converting pyrroline-5-carboxylate to glutamate. Deficiency of this enzyme is associated with type II hyperprolinemia, an autosomal recessive disorder characterized by accumulation of delta-1-pyrroline-5-carboxylate (P5C) and proline. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene. |
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