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ALDH4A1 Full-Length MS Protein Standard

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Product Description


NameALDH4A1 Full-Length MS Protein Standard
Cat#CPFL304884
Protein Namealdehyde dehydrogenase 4 family, member A1
SymbolALDH4A1
SynonymsALDH4; P5CD; P5CDh
AccessionNM_170726
Cytogenetic1p36
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
DescriptionALDH4A1 Full-Length MS Protein Standard (NP_733844), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This protein belongs to the aldehyde dehydrogenase family of proteins. This enzyme is a mitochondrial matrix NAD-dependent dehydrogenase which catalyzes the second step of the proline degradation pathway, converting pyrroline-5-carboxylate to glutamate. Deficiency of this enzyme is associated with type II hyperprolinemia, an autosomal recessive disorder characterized by accumulation of delta-1-pyrroline-5-carboxylate (P5C) and proline. Alternatively spliced transcript variants encoding different isoforms have been identified for this gene.

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