BACE2 Full-Length MS Protein Standard


Product Description:

Name BACE2 Full-Length MS Protein Standard
Cat# CPFL304860
Protein Namebeta-site APP-cleaving enzyme 2
SymbolBACE2
SynonymsAEPLC; ALP56; ASP1; ASP21; BAE2; CDA13; CEAP1; DRAP
AccessionNM_012105
Cytogenetic21q22.3
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW49.8 kDa
Expression TrueORF CloneRC204860
DescriptionBACE2 Full-Length MS Protein Standard (NP_036237), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. This gene encodes an integral membrane glycoprotein that functions as an aspartic protease. The encoded protein cleaves amyloid precursor protein into amyloid beta peptide, which is a critical step in the etiology of Alzheimers disease and Down syndrome. The protein precursor is further processed into an active mature peptide. Alternative splicing results in multiple transcript variants.

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