GZMA Full-Length MS Protein Standard
Product Description:
| Name |
GZMA Full-Length MS Protein Standard |
| Cat# |
CPFL304852 |
| Protein Name | granzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3) |
| Symbol | GZMA |
| Synonyms | CTLA3; HFSP |
| Accession | NM_006144 |
| Cytogenetic | 5q11-q12 |
| Amino Acid Labeled | [U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys |
| Chemical Purity | > 80% as determined by SDS-PAGE and Coomassie blue staining |
| Expression Host | Human HEK293 cells |
| Predicted MW | 28.8 kDa |
| Expression TrueORF Clone | RC204852 |
| Description | GZMA Full-Length MS Protein Standard (NP_006135), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface nonself antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein described here is a T cell- and natural killer cell-specific serine protease that may function as a common component necessary for lysis of target cells by cytotoxic T lymphocytes and natural killer cells. |
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