GZMA Full-Length MS Protein Standard


Product Description:

Name GZMA Full-Length MS Protein Standard
Cat# CPFL304852
Protein Namegranzyme A (granzyme 1, cytotoxic T-lymphocyte-associated serine esterase 3)
SymbolGZMA
SynonymsCTLA3; HFSP
AccessionNM_006144
Cytogenetic5q11-q12
Amino Acid Labeled[U- 13C6, 15N4]-L-Arg and [U- 13C6, 15N2]-L-Lys
Chemical Purity> 80% as determined by SDS-PAGE and Coomassie blue staining
Expression HostHuman HEK293 cells
Predicted MW28.8 kDa
Expression TrueORF CloneRC204852
DescriptionGZMA Full-Length MS Protein Standard (NP_006135), Labeled with [U- 13C6, 15N4]-L-Arginine and [U- 13C6, 15N2]-L-Lysine, was produced in human 293 cells (HEK293) with fully chemically defined cell culture medium to obtain incorporation efficiency at Creative-Proteomics. Cytolytic T lymphocytes (CTL) and natural killer (NK) cells share the remarkable ability to recognize, bind, and lyse specific target cells. They are thought to protect their host by lysing cells bearing on their surface nonself antigens, usually peptides or proteins resulting from infection by intracellular pathogens. The protein described here is a T cell- and natural killer cell-specific serine protease that may function as a common component necessary for lysis of target cells by cytotoxic T lymphocytes and natural killer cells.

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